Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN97007.1COG0591 Na+/proline symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (537 aa)    
Predicted Functional Partners:
AEN97006.1
COG0477 Permeases of the major facilitator superfamily.
  
  
 0.699
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
   
  
 0.696
caiC
Putative crotonobetaine/carnitine-CoA ligase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
  
 0.503
AEN97009.1
COG1960 Acyl-CoA dehydrogenases.
  
  
 0.484
AEN96934.1
Hypothetical protein; COG0733 Na+-dependent transporters of the SNF family; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
 
  
 0.483
AEN96120.1
COG0642 Signal transduction histidine kinase.
  
 
 0.458
AEN96060.1
Amino acid carrier protein; COG1115 Na+/alanine symporter.
  
   
 0.438
AEN97041.1
COG0067 Glutamate synthase domain 1.
   
  
 0.420
AEN95559.1
Signaling protein; COG2199 FOG: GGDEF domain.
   
  
 0.416
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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