Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN97091.1Cell wall binding domain-containing protein; COG1387 Histidinol phosphatase and related hydrolases of the PHP family. (2128 aa)    
Predicted Functional Partners:
hisI
COG0107 Imidazoleglycerol-phosphate synthase; In the C-terminal section; belongs to the PRA-PH family.
  
  
 0.858
AEN97090.1
YibE/F-like protein; COG5438 Predicted multitransmembrane protein.
 
     0.792
AEN97092.1
Hypothetical protein.
       0.584
AEN97261.1
Hypothetical protein; COG3867 Arabinogalactan endo-1,4-beta-galactosidase.
  
     0.578
AEN97093.1
5-aminoimidazole-4-carboxamide ribonucleotide transformylase; COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful).
       0.536
AEN97094.1
Hypothetical protein; COG3363 Archaeal IMP cyclohydrolase.
       0.522
AEN98108.1
Hypothetical protein.
  
     0.480
hisB
COG0131 Imidazoleglycerol-phosphate dehydratase.
  
  
 0.462
AEN97041.1
COG0067 Glutamate synthase domain 1.
  
  
 0.446
AEN95663.1
Helix-turn-helix domain-containing protein; COG1396 Predicted transcriptional regulators.
  
     0.440
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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