Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN97104.1Hypothetical protein; COG0824 Predicted thioesterase. (154 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
       0.723
AEN97103.1
Peptidase, M24 family protein; COG0006 Xaa-Pro aminopeptidase.
       0.665
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.612
AEN97100.1
COG0849 Actin-like ATPase involved in cell division.
       0.574
AEN97099.1
Hypothetical protein; COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I.
       0.546
AEN97921.1
COG0331 (acyl-carrier-protein) S-malonyltransferase.
  
  
 0.529
AEN97938.1
COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
     
 0.501
AEN96504.1
COG1536 Flagellar motor switch protein.
    
   0.480
accA
acetyl-coA carboxylase carboxyl transferase subunit beta/alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
  
  
 0.453
AEN97105.1
Hypothetical protein.
       0.443
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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