Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (534 aa)    
Predicted Functional Partners:
AEN95785.1
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.936
AEN96380.1
Pyruvate phosphate dikinase; COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
     
 0.936
eno-2
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.920
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.920
AEN96794.1
COG5016 Pyruvate/oxaloacetate carboxyltransferase.
    
 0.918
AEN96795.1
Sodium ion-translocating decarboxylase, beta subunit; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD).
    
 0.913
AEN96688.1
2-isopropylmalate synthase; COG0119 Isopropylmalate/homocitrate/citramalate synthases.
   
 
 0.910
AEN96709.1
COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.910
AEN97856.1
COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.910
AEN98047.1
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.907
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.