Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN97216.1Hypothetical protein; COG1396 Predicted transcriptional regulators. (122 aa)    
Predicted Functional Partners:
AEN97168.1
Hypothetical protein; COG1396 Predicted transcriptional regulators.
  
     0.739
AEN97213.1
Sensor protein; COG0642 Signal transduction histidine kinase.
 
     0.675
AEN97846.1
Hypothetical protein; COG2200 FOG: EAL domain.
  
     0.661
AEN97215.1
Hypothetical protein.
 
   0.633
AEN97214.1
COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
     0.629
AEN97222.1
Hypothetical protein.
  
     0.594
AEN97211.1
Hypothetical protein.
 
    0.591
AEN97210.1
Hypothetical protein; COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component.
 
    0.557
AEN97212.1
Lantibiotic ABC transporter ATP-binding protein; COG1131 ABC-type multidrug transport system, ATPase component.
 
     0.534
AEN97831.1
Hypothetical protein.
  
     0.525
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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