Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN97247.1Hypothetical protein; COG1929 Glycerate kinase; Belongs to the glycerate kinase type-1 family. (375 aa)    
Predicted Functional Partners:
gpmI
Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
     
 0.913
AEN95651.1
Proposed homoserine kinase; COG3635 Predicted phosphoglycerate mutase, AP superfamily.
     
  0.900
tadA
Cytidine and deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
 
 
    0.673
birA
Putative transcriptional repressor of the biotin operon birA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
   
    0.593
AEN95785.1
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.505
AEN97248.1
Hypothetical protein; COG1002 Type II restriction enzyme, methylase subunits.
       0.425
AEN97249.1
Hypothetical protein; COG1002 Type II restriction enzyme, methylase subunits.
       0.425
AEN97946.1
COG1052 Lactate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
   
 0.423
AEN98306.1
PTS system, fructose-specific, IIABC component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
     
 0.421
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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