Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN97341.1CoA-substrate-specific enzyme activase; COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain). (1280 aa)    
Predicted Functional Partners:
AEN96355.1
Putative R-2-hydroxyglutaryl-CoA dehydratase subunit/R-2-hydroxyglutaryl-CoA dehydratase activase; COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain).
 
   
0.642
AEN97715.1
COG4905 Predicted membrane protein.
 
     0.505
AEN97343.1
COG0642 Signal transduction histidine kinase.
       0.492
AEN97342.1
RNA binding S1 domain protein; COG0539 Ribosomal protein S1.
       0.491
AEN97344.1
Two component transcriptional regulator, winged helix family protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
       0.491
AEN95141.1
COG4905 Predicted membrane protein.
 
     0.489
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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