Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN97438.1COG0491 Zn-dependent hydrolases, including glyoxylases. (209 aa)    
Predicted Functional Partners:
AEN97014.1
COG0491 Zn-dependent hydrolases, including glyoxylases.
  
  
 
0.916
AEN97606.1
Glyoxalase/bleomycin resistance protein/dioxygenase; COG0346 Lactoylglutathione lyase and related lyases.
  
 0.915
AEN97439.1
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
    0.713
AEN98071.1
Hypothetical protein; COG0607 Rhodanese-related sulfurtransferase; Belongs to the TtcA family.
  
 
 0.543
AEN97441.1
COG1476 Predicted transcriptional regulators.
  
    0.541
AEN97440.1
Guanosine monophosphate synthetase GuaA; COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins.
       0.533
AEN97437.1
COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases.
     
 0.530
groS
Co-chaperonin GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
    
 
 0.457
AEN97442.1
Hypothetical protein.
       0.447
pnp
Polynucleotide phosphorylase/polyadenylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
   
 0.420
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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