| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEN95131.1 | AEN96387.1 | RHOM_00010 | RHOM_06340 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Exodeoxyribonuclease; COG0708 Exonuclease III. | 0.925 |
| AEN95131.1 | AEN97483.1 | RHOM_00010 | RHOM_11875 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | A/G-specific DNA glycosylase; Adenine glycosylase active on G-A mispairs. | 0.826 |
| AEN95131.1 | guaB | RHOM_00010 | RHOM_05275 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.483 |
| AEN95131.1 | metG | RHOM_00010 | RHOM_00480 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.431 |
| AEN95131.1 | mutL | RHOM_00010 | RHOM_07720 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.953 |
| AEN95131.1 | polA | RHOM_00010 | RHOM_09955 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.989 |
| AEN96387.1 | AEN95131.1 | RHOM_06340 | RHOM_00010 | Exodeoxyribonuclease; COG0708 Exonuclease III. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.925 |
| AEN96387.1 | AEN97337.1 | RHOM_06340 | RHOM_11140 | Exodeoxyribonuclease; COG0708 Exonuclease III. | COG3663 G:T/U mismatch-specific DNA glycosylase. | 0.567 |
| AEN96387.1 | AEN97483.1 | RHOM_06340 | RHOM_11875 | Exodeoxyribonuclease; COG0708 Exonuclease III. | A/G-specific DNA glycosylase; Adenine glycosylase active on G-A mispairs. | 0.914 |
| AEN96387.1 | guaB | RHOM_06340 | RHOM_05275 | Exodeoxyribonuclease; COG0708 Exonuclease III. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.425 |
| AEN96387.1 | metG | RHOM_06340 | RHOM_00480 | Exodeoxyribonuclease; COG0708 Exonuclease III. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.588 |
| AEN96387.1 | polA | RHOM_06340 | RHOM_09955 | Exodeoxyribonuclease; COG0708 Exonuclease III. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.831 |
| AEN97337.1 | AEN96387.1 | RHOM_11140 | RHOM_06340 | COG3663 G:T/U mismatch-specific DNA glycosylase. | Exodeoxyribonuclease; COG0708 Exonuclease III. | 0.567 |
| AEN97337.1 | AEN97483.1 | RHOM_11140 | RHOM_11875 | COG3663 G:T/U mismatch-specific DNA glycosylase. | A/G-specific DNA glycosylase; Adenine glycosylase active on G-A mispairs. | 0.862 |
| AEN97483.1 | AEN95131.1 | RHOM_11875 | RHOM_00010 | A/G-specific DNA glycosylase; Adenine glycosylase active on G-A mispairs. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.826 |
| AEN97483.1 | AEN96387.1 | RHOM_11875 | RHOM_06340 | A/G-specific DNA glycosylase; Adenine glycosylase active on G-A mispairs. | Exodeoxyribonuclease; COG0708 Exonuclease III. | 0.914 |
| AEN97483.1 | AEN97337.1 | RHOM_11875 | RHOM_11140 | A/G-specific DNA glycosylase; Adenine glycosylase active on G-A mispairs. | COG3663 G:T/U mismatch-specific DNA glycosylase. | 0.862 |
| AEN97483.1 | AEN97484.1 | RHOM_11875 | RHOM_11880 | A/G-specific DNA glycosylase; Adenine glycosylase active on G-A mispairs. | COG0436 Aspartate/tyrosine/aromatic aminotransferase. | 0.719 |
| AEN97483.1 | AEN97485.1 | RHOM_11875 | RHOM_11885 | A/G-specific DNA glycosylase; Adenine glycosylase active on G-A mispairs. | 3-hydroxybutyryl-coA dehydratase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.500 |
| AEN97483.1 | AEN97487.1 | RHOM_11875 | RHOM_11895 | A/G-specific DNA glycosylase; Adenine glycosylase active on G-A mispairs. | Cyclomaltodextrinase; COG0366 Glycosidases. | 0.451 |
