Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN97505.1COG0463 Glycosyltransferases involved in cell wall biogenesis. (313 aa)    
Predicted Functional Partners:
AEN97504.1
Teichoic acid glycosylation protein; COG2246 Predicted membrane protein.
 
  
 0.861
AEN97508.1
Mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase.
  
  
 0.782
AEN97503.1
Hypothetical protein.
       0.781
AEN97506.1
COG0019 Diaminopimelate decarboxylase.
  
    0.774
AEN97507.1
COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ).
       0.774
fcl
GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
  
    0.738
AEN97502.1
COG3274 Uncharacterized protein conserved in bacteria.
  
    0.654
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
  
 0.551
AEN97494.1
Undecaprenyl-phosphate glucose phosphotransferase; COG2148 Sugar transferases involved in lipopolysaccharide synthesis.
  
  
 0.446
AEN97500.1
Methicillin resistance protein; COG4219 Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component.
       0.409
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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