STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (344 aa)    
Predicted Functional Partners:
fcl
GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
 0.998
AEN97508.1
Mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase.
 
 
 0.984
AEN97494.1
Undecaprenyl-phosphate glucose phosphotransferase; COG2148 Sugar transferases involved in lipopolysaccharide synthesis.
  
  
 0.969
rplD
50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
 
      0.736
AEN95266.1
UDP-4-dehydro-6-deoxy-2-acetamido-D-glucose 4-reductase; COG1086 Predicted nucleoside-diphosphate sugar epimerases.
  
  
 0.721
AEN97558.1
Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; COG2148 Sugar transferases involved in lipopolysaccharide synthesis.
  
  
 0.660
AEN97576.1
Undecaprenyl-phosphate galactose phosphotransferase; COG2148 Sugar transferases involved in lipopolysaccharide synthesis.
  
  
 0.660
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
    
   0.625
AEN97504.1
Teichoic acid glycosylation protein; COG2246 Predicted membrane protein.
       0.559
AEN97511.1
Transcriptional regulator, AraC family protein; COG2207 AraC-type DNA-binding domain-containing proteins.
       0.557
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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