Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN97533.1Hypothetical protein; COG4778 ABC-type phosphonate transport system, ATPase component. (851 aa)    
Predicted Functional Partners:
AEN95712.1
Ribonuclease Ph; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
   
   0.796
AEN97575.1
Hypothetical protein; COG0489 ATPases involved in chromosome partitioning.
 
    0.795
AEN97515.1
Glycosyl transferase family protein.
  
    0.773
AEN95224.1
Hypothetical protein.
  
     0.770
AEN95236.1
Hypothetical protein.
  
     0.769
AEN95270.1
Multimeric flavodoxin domain-containing protein; COG0438 Glycosyltransferase.
  
     0.769
AEN97696.1
COG1112 Superfamily I DNA and RNA helicases and helicase subunits.
 
    0.759
AEN97794.1
Hypothetical protein.
  
     0.759
AEN97345.1
Hypothetical protein.
 
   
 0.756
AEN97908.1
Replisome organizer, phage associated protein.
 
     0.756
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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