Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN97540.1Cell wall hydrolase/autolysin; COG5279 Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain. (935 aa)    
Predicted Functional Partners:
AEN97541.1
N-acetylmuramidase/lysin; COG0860 N-acetylmuramoyl-L-alanine amidase.
 
   
0.563
AEN97538.1
IS66 Orf2 family protein; COG3436 Transposase and inactivated derivatives.
       0.508
AEN97539.1
Hypothetical protein.
       0.508
AEN95227.1
ABC-2 type transporter; COG0842 ABC-type multidrug transport system, permease component.
  
     0.480
AEN95226.1
Hypothetical protein; COG0842 ABC-type multidrug transport system, permease component.
  
     0.465
AEN97557.1
Glycosyltransferase (cell wall biogenesis) Cps9G; COG0463 Glycosyltransferases involved in cell wall biogenesis.
  
 
 0.454
AEN97704.1
FRG domain-containing protein.
  
     0.444
AEN97542.1
Amidohydrolase; COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.
       0.431
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
Server load: low (20%) [HD]