Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN97541.1N-acetylmuramidase/lysin; COG0860 N-acetylmuramoyl-L-alanine amidase. (1786 aa)    
Predicted Functional Partners:
AEN98255.1
Rhomboid family protein; COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid).
   
   0.762
AEN97542.1
Amidohydrolase; COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold.
       0.689
AEN97704.1
FRG domain-containing protein.
  
     0.645
AEN97543.1
Na+/glutamate symporter-like protein; COG0786 Na+/glutamate symporter.
  
    0.592
AEN97540.1
Cell wall hydrolase/autolysin; COG5279 Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain.
 
   
0.563
AEN97544.1
Hypothetical protein; COG5263 FOG: Glucan-binding domain (YG repeat).
       0.549
AEN97545.1
Coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein.
       0.528
AEN97546.1
Hypothetical protein.
       0.528
AEN96673.1
Hypothetical protein; COG0457 FOG: TPR repeat.
  
     0.443
AEN95520.1
Efflux ABC transporter permease; COG0577 ABC-type antimicrobial peptide transport system, permease component.
 
    0.438
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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