Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN97578.1Type 12 methyltransferase; COG0500 SAM-dependent methyltransferases. (279 aa)    
Predicted Functional Partners:
AEN97577.1
Hypothetical protein.
     0.991
AEN97579.1
COG1134 ABC-type polysaccharide/polyol phosphate transport system, ATPase component.
 
     0.800
AEN97575.1
Hypothetical protein; COG0489 ATPases involved in chromosome partitioning.
 
     0.780
AEN97580.1
Wzm; COG1682 ABC-type polysaccharide/polyol phosphate export systems, permease component.
 
     0.756
AEN97576.1
Undecaprenyl-phosphate galactose phosphotransferase; COG2148 Sugar transferases involved in lipopolysaccharide synthesis.
       0.747
AEN97573.1
Hypothetical protein.
       0.721
AEN97574.1
Hypothetical protein.
       0.721
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 
 0.708
AEN96217.1
Hypothetical protein; COG1559 Predicted periplasmic solute-binding protein.
  
     0.683
AEN97569.1
Hypothetical protein; COG0438 Glycosyltransferase.
 
     0.677
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
Server load: low (28%) [HD]