Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN97637.1Hypothetical protein. (265 aa)    
Predicted Functional Partners:
AEN97638.1
Hypothetical protein.
 
    0.945
AEN97639.1
COG0739 Membrane proteins related to metalloendopeptidases.
 
     0.804
AEN97640.1
LrgB family protein; COG1346 Putative effector of murein hydrolase.
       0.559
AEN97641.1
Holin-like protein; COG1380 Putative effector of murein hydrolase LrgA.
       0.559
AEN97636.1
COG0527 Aspartokinases; Belongs to the aspartokinase family.
       0.524
AEN97635.1
COG1376 Uncharacterized protein conserved in bacteria.
       0.491
AEN97964.1
MATE efflux family protein; COG0534 Na+-driven multidrug efflux pump.
  
     0.472
AEN97642.1
Hypothetical protein; COG0642 Signal transduction histidine kinase.
     
 0.417
AEN96742.1
Prephenate dehydratase; COG1605 Chorismate mutase.
  
    0.413
AEN96858.1
Transporter; COG2244 Membrane protein involved in the export of O-antigen and teichoic acid.
  
     0.410
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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