Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN97672.1COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (301 aa)    
Predicted Functional Partners:
AEN97673.1
Hypothetical protein.
       0.779
AEN97674.1
Putative small membrane protein.
       0.773
AEN97041.1
COG0067 Glutamate synthase domain 1.
     
 0.598
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.566
AEN97675.1
Hypothetical protein; COG1228 Imidazolonepropionase and related amidohydrolases.
  
    0.553
AEN97671.1
Hypothetical protein.
       0.478
AEN97676.1
COG1102 Cytidylate kinase.
       0.455
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.440
rpoZ
Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
 
 0.432
AEN97680.1
LysR family regulatory protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
 
    
0.418
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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