Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN97687.1Spore photoproduct. (304 aa)    
Predicted Functional Partners:
AEN97686.1
Spore photoproduct; COG1533 DNA repair photolyase.
   
 0.974
AEN97685.1
Putative short-chain dehydrogenases/reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
     0.922
AEN97688.1
Hydrogenase accessory protein HypB2; COG0523 Putative GTPases (G3E family).
       0.780
AEN97684.1
Hypothetical protein; COG0534 Na+-driven multidrug efflux pump.
       0.762
AEN97689.1
COG4690 Dipeptidase.
       0.762
AEN97464.1
Spore germination protein-like protein YndE.
  
     0.641
AEN97041.1
COG0067 Glutamate synthase domain 1.
     
 0.566
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.527
AEN97353.1
COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.
     
 0.527
AEN97682.1
Hypothetical protein; COG0071 Molecular chaperone (small heat shock protein); Belongs to the small heat shock protein (HSP20) family.
 
     0.525
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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