node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEN96870.1 | spoVG | RHOM_08795 | RHOM_13150 | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | Stage V sporulation protein G; Could be involved in septation. | 0.500 |
AEN97739.1 | glgC | RHOM_13155 | RHOM_13160 | COG0448 ADP-glucose pyrophosphorylase; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.997 |
AEN97739.1 | glmU | RHOM_13155 | RHOM_13145 | COG0448 ADP-glucose pyrophosphorylase; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains). | 0.467 |
AEN97739.1 | mfd | RHOM_13155 | RHOM_13135 | COG0448 ADP-glucose pyrophosphorylase; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.421 |
AEN97739.1 | murC | RHOM_13155 | RHOM_13165 | COG0448 ADP-glucose pyrophosphorylase; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.465 |
AEN97739.1 | pth | RHOM_13155 | RHOM_13140 | COG0448 ADP-glucose pyrophosphorylase; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.426 |
AEN97739.1 | spoVG | RHOM_13155 | RHOM_13150 | COG0448 ADP-glucose pyrophosphorylase; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | Stage V sporulation protein G; Could be involved in septation. | 0.714 |
glgC | AEN97739.1 | RHOM_13160 | RHOM_13155 | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | COG0448 ADP-glucose pyrophosphorylase; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.997 |
glgC | glmU | RHOM_13160 | RHOM_13145 | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains). | 0.468 |
glgC | mfd | RHOM_13160 | RHOM_13135 | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.418 |
glgC | murC | RHOM_13160 | RHOM_13165 | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.466 |
glgC | pth | RHOM_13160 | RHOM_13140 | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.422 |
glgC | spoVG | RHOM_13160 | RHOM_13150 | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | Stage V sporulation protein G; Could be involved in septation. | 0.714 |
glmU | AEN97739.1 | RHOM_13145 | RHOM_13155 | COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains). | COG0448 ADP-glucose pyrophosphorylase; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.467 |
glmU | glgC | RHOM_13145 | RHOM_13160 | COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains). | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. | 0.468 |
glmU | mfd | RHOM_13145 | RHOM_13135 | COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains). | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.823 |
glmU | murC | RHOM_13145 | RHOM_13165 | COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains). | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.862 |
glmU | pth | RHOM_13145 | RHOM_13140 | COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains). | aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.796 |
glmU | spoVG | RHOM_13145 | RHOM_13150 | COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains). | Stage V sporulation protein G; Could be involved in septation. | 0.474 |
gyrB | rpoB | RHOM_00025 | RHOM_00980 | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.767 |