Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN97752.1Hypothetical protein; COG0659 Sulfate permease and related transporters (MFS superfamily). (708 aa)    
Predicted Functional Partners:
sbcD
Nuclease SbcCD, D subunit; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
  
   0.625
AEN97930.1
Metallophosphoesterase; COG0420 DNA repair exonuclease.
   
   0.625
AEN97753.1
Methyl-accepting chemotaxis sensory transducer with Cache sensor; COG0840 Methyl-accepting chemotaxis protein.
       0.559
AEN97754.1
Hypothetical protein.
       0.532
AEN96227.1
COG0236 Acyl carrier protein.
    
 
 0.492
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 
 0.492
acpP-2
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
    
 
 0.492
AEN97938.1
COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
 
 
 0.471
AEN98121.1
COG3513 Uncharacterized protein conserved in bacteria.
  
     0.454
AEN98079.1
Hypothetical protein; COG2755 Lysophospholipase L1 and related esterases.
  
     0.432
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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