Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN97823.1COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (230 aa)    
Predicted Functional Partners:
AEN97822.1
Sensor protein; COG0642 Signal transduction histidine kinase.
 
   0.960
AEN97820.1
Lantibiotic ABC transporter permease; COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component.
 
     0.855
AEN97819.1
COG0842 ABC-type multidrug transport system, permease component.
 
     0.851
AEN97213.1
Sensor protein; COG0642 Signal transduction histidine kinase.
 
   0.832
AEN97821.1
Lantibiotic ABC transporter ATP-binding protein; COG1131 ABC-type multidrug transport system, ATPase component.
 
   
 0.832
AEN97824.1
Hypothetical protein.
  
   0.775
AEN95379.1
PAS/PAC sensor hybrid histidine kinase; COG0784 FOG: CheY-like receiver.
  
 
 0.749
AEN97212.1
Lantibiotic ABC transporter ATP-binding protein; COG1131 ABC-type multidrug transport system, ATPase component.
 
   
 0.684
AEN95209.1
Two-component system OmpR family sensor kinase; COG0642 Signal transduction histidine kinase.
 
 
 0.652
AEN96314.1
COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.
 
 
 0.652
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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