Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN97849.1COG0656 Aldo/keto reductases, related to diketogulonate reductase. (279 aa)    
Predicted Functional Partners:
AEN97938.1
COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
  
 
 0.674
AEN97353.1
COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain.
   
 0.669
AEN98424.1
COG0789 Predicted transcriptional regulators.
     0.615
AEN95594.1
Putative oxidoreductase protein; COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).
  
 
 0.587
AEN98328.1
COG0716 Flavodoxins.
 
     0.560
AEN97850.1
COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
       0.526
AEN96793.1
Hypothetical protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
  
 0.480
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
   
 
 0.461
AEN97848.1
parB-like partition protein; COG1475 Predicted transcriptional regulators; Belongs to the ParB family.
  
    0.427
AEN95751.1
4-methyl-5(beta-hydroxyethyl)-thiazole monophosphate synthesis protein; COG0693 Putative intracellular protease/amidase.
  
  
 0.419
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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