Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN97886.1Diguanylate cyclase; COG2199 FOG: GGDEF domain. (382 aa)    
Predicted Functional Partners:
AEN96391.1
Diguanylate cyclase/phosphodiesterase; COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.
 
  
 0.879
AEN98437.1
COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.
 
  
 0.856
AEN97310.1
EAL domain-containing protein; COG2200 FOG: EAL domain.
  
    0.806
AEN97992.1
Sensory transduction protein kinase; COG2200 FOG: EAL domain.
  
    0.806
AEN95849.1
Signaling protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
  
    0.805
AEN95792.1
Two-component system, PleD related family, response regulator; COG2199 FOG: GGDEF domain.
  
    0.802
AEN95392.1
Two-component system, PleD related family, response regulator; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
  
    0.795
AEN96422.1
PAS/PAC sensor(s)-containing diguanylate cyclase/phosphodiesterase; COG2199 FOG: GGDEF domain.
  
     0.774
AEN97885.1
Diguanylate cyclase; COG2199 FOG: GGDEF domain.
 
    
0.769
AEN95827.1
HD-GYP domain-containing protein; COG2206 HD-GYP domain.
 
 
 0.749
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.