Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN97938.1COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. (644 aa)    
Predicted Functional Partners:
AEN95550.1
COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
  
 0.968
AEN97745.1
COG0462 Phosphoribosylpyrophosphate synthetase; Belongs to the ribose-phosphate pyrophosphokinase family.
  
 0.948
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.936
AEN95678.1
COG2086 Electron transfer flavoprotein, beta subunit.
  
 
 0.886
AEN97011.1
COG2086 Electron transfer flavoprotein, beta subunit.
  
 
 0.886
AEN97017.1
COG2086 Electron transfer flavoprotein, beta subunit.
  
 
 0.886
tuf
Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
  
  
 0.885
AEN95679.1
COG2025 Electron transfer flavoprotein, alpha subunit.
  
 
 0.876
AEN97010.1
COG2025 Electron transfer flavoprotein, alpha subunit.
  
 
 0.876
AEN97018.1
COG2025 Electron transfer flavoprotein, alpha subunit.
  
 
 0.876
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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