Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN97940.1COG0546 Predicted phosphatases. (217 aa)    
Predicted Functional Partners:
AEN95143.1
COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain.
 
      0.646
hisI
COG0107 Imidazoleglycerol-phosphate synthase; In the C-terminal section; belongs to the PRA-PH family.
  
  
 0.601
AEN97941.1
COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases).
       0.575
AEN96458.1
Lactate utilization protein B/C.
 
      0.560
AEN97939.1
Methyl-accepting chemotaxis sensory transducer with Cache sensor; COG0840 Methyl-accepting chemotaxis protein.
       0.496
AEN98346.1
Radical SAM domain-containing protein; COG0535 Predicted Fe-S oxidoreductases.
  
    0.490
AEN96087.1
Pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit.
     
 0.455
AEN97942.1
Sulfatase; COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily.
       0.436
ribBA
GTP cyclohydrolase II/3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
  
  
 0.415
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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