Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN98046.1Two-component system, response regulator YesN; COG2207 AraC-type DNA-binding domain-containing proteins. (407 aa)    
Predicted Functional Partners:
AEN98459.1
Xylan 1,4-beta-xylosidase; COG2207 AraC-type DNA-binding domain-containing proteins.
  
     0.752
AEN95948.1
Integral membrane sensor signal transduction histidine kinase; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.
 
 
  0.716
AEN97416.1
Signal transduction histidine kinase, LytS; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.
 
 
  0.714
AEN97300.1
L-rhamnose operon transcriptional activator; COG2207 AraC-type DNA-binding domain-containing proteins.
  
     0.676
AEN97233.1
Two-component system response regulator YesN; COG2207 AraC-type DNA-binding domain-containing proteins.
  
     0.666
AEN95832.1
Histidine kinase; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.
  
 
  0.660
AEN95903.1
Multi-sensor signal transduction histidine kinase; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.
  
 
  0.660
AEN96271.1
Hypothetical protein; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.
  
 
  0.660
AEN96614.1
Two component system histidine kinase; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.
  
 
  0.660
AEN98045.1
Glycoside/pentoside/hexuronide:cation symporter, GPH family protein; COG2211 Na+/melibiose symporter and related transporters.
 
     0.608
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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