Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN98050.1Hypothetical protein; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily. (300 aa)    
Predicted Functional Partners:
AEN98051.1
Ectoine/hydroxyectoine ABC transporter ATP-binding protein; COG1126 ABC-type polar amino acid transport system, ATPase component.
       0.779
AEN98052.1
Hypothetical protein; COG0637 Predicted phosphatase/phosphohexomutase.
       0.779
thiE
Hypothetical protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
       0.773
thiM
Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family.
       0.773
AEN98049.1
Hypothetical protein; COG1247 Sortase and related acyltransferases.
  
    0.511
AEN98048.1
COG0598 Mg2+ and Co2+ transporters.
  
    0.467
AEN98055.1
Permease; COG0628 Predicted permease.
  
  
 0.421
ispD
4-diphosphocytidyl-2-methylerithritol synthase (sugar nucleotide phosphorylase family) protein; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
     
 0.415
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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