STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN98113.1Fur family transcriptional regulator, ferric uptake regulator; COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family. (135 aa)    
Predicted Functional Partners:
AEN98112.1
Hypothetical protein.
  
  
 0.780
AEN98115.1
Peroxiredoxin (alkyl hydroperoxide reductase subunit C); COG1225 Peroxiredoxin.
 
   
 0.626
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.591
AEN98111.1
Putative two-component system response regulator; COG2206 HD-GYP domain.
 
     0.588
AEN98114.1
COG3022 Uncharacterized protein conserved in bacteria; Belongs to the UPF0246 family.
       0.497
AEN98116.1
Hypothetical protein.
       0.497
sigA
RpoD family RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.421
AEN97041.1
COG0067 Glutamate synthase domain 1.
     
 0.405
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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