Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN98132.1Hypothetical protein. (60 aa)    
Predicted Functional Partners:
secA
Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
    
 
 0.829
AEN98133.1
Hypothetical protein.
       0.773
tig
Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily.
    
 
 0.702
AEN97460.1
Trigger factor; COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor).
    
 
 0.702
AEN95202.1
Hypothetical protein; COG0226 ABC-type phosphate transport system, periplasmic component.
  
  
 0.586
AEN96498.1
COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.
  
    0.529
AEN98134.1
CHU large protein; COG3507 Beta-xylosidase; Belongs to the glycosyl hydrolase 43 family.
       0.519
pstB
Phosphate transporter ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
  
  
 0.515
AEN97103.1
Peptidase, M24 family protein; COG0006 Xaa-Pro aminopeptidase.
    
  0.515
AEN95206.1
Phosphate uptake regulator, PhoU; Plays a role in the regulation of phosphate uptake.
  
  
 0.491
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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