Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AEN98167.1Beta-lactamase; COG4219 Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component. (598 aa)    
Predicted Functional Partners:
AEN98166.1
Penicillinase repressor; COG3682 Predicted transcriptional regulator.
 
 
 0.997
AEN97501.1
Hypothetical protein; COG3682 Predicted transcriptional regulator.
 
 
 0.981
AEN97500.1
Methicillin resistance protein; COG4219 Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component.
 
  
 
0.920
AEN98170.1
Hypothetical protein.
  
     0.745
AEN98173.1
Peptidoglycan glycosyltransferase; COG0768 Cell division protein FtsI/penicillin-binding protein 2.
 
   
 0.512
AEN98165.1
Transcriptional regulator, XRE family protein; COG1396 Predicted transcriptional regulators.
       0.429
AEN97860.1
Conjugative transposon FtsK/SpoIIIE-related protein.
  
     0.403
AEN98295.1
Hypothetical protein.
  
     0.400
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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