Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN98180.1Hypothetical protein; COG1396 Predicted transcriptional regulators. (120 aa)    
Predicted Functional Partners:
AEN98183.1
Hypothetical protein.
       0.758
AEN98182.1
Hypothetical protein.
       0.746
AEN98181.1
DNA topoisomerase III; COG0550 Topoisomerase IA.
       0.741
AEN98186.1
Hypothetical protein; COG1174 ABC-type proline/glycine betaine transport systems, permease component.
       0.701
AEN98184.1
Peptidase, M23 family protein; COG0739 Membrane proteins related to metalloendopeptidases.
       0.685
AEN98185.1
Hypothetical protein; COG3451 Type IV secretory pathway, VirB4 components.
       0.685
AEN98179.1
COG0827 Adenine-specific DNA methylase.
       0.641
AEN98187.1
Hypothetical protein.
       0.525
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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