Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN98255.1Rhomboid family protein; COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid). (394 aa)    
Predicted Functional Partners:
AEN95711.1
COG0860 N-acetylmuramoyl-L-alanine amidase.
   
   0.762
AEN97541.1
N-acetylmuramidase/lysin; COG0860 N-acetylmuramoyl-L-alanine amidase.
   
   0.762
AEN96776.1
COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
  
  
 0.698
AEN98256.1
Hypothetical protein; COG1716 FOG: FHA domain.
 
     0.663
AEN98254.1
Hypothetical protein; COG0655 Multimeric flavodoxin WrbA.
       0.657
AEN98258.1
Hypothetical protein; COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases.
 
   
 0.622
AEN98247.1
Membrane protease subunit, stomatin/prohibitin-like protein; COG0330 Membrane protease subunits, stomatin/prohibitin homologs.
   
 0.586
AEN98259.1
Hypothetical protein.
 
     0.558
AEN98257.1
Hypothetical protein.
       0.547
AEN98260.1
Hypothetical protein.
 
    0.421
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.