Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN98256.1Hypothetical protein; COG1716 FOG: FHA domain. (411 aa)    
Predicted Functional Partners:
AEN97109.1
COG0515 Serine/threonine protein kinase.
 
 
 
 0.971
AEN98259.1
Hypothetical protein.
 
     0.845
AEN98260.1
Hypothetical protein.
 
   
 0.826
AEN98273.1
Serine/threonine protein kinase fused to TPR repeats domain protein; COG0515 Serine/threonine protein kinase.
 
 
 
 0.822
AEN98258.1
Hypothetical protein; COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases.
 
   
 0.800
AEN95131.1
DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 
 0.789
AEN96517.1
Flagellar motor switch protein; COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation.
  
 
 0.787
AEN98274.1
Hypothetical protein.
   
 
 0.785
AEN98257.1
Hypothetical protein.
       0.773
AEN97621.1
Hypothetical protein.
  
  
 0.764
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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