Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN98306.1PTS system, fructose-specific, IIABC component; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). (636 aa)    
Predicted Functional Partners:
AEN98307.1
COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
 
 0.999
AEN98308.1
Transcription repressor of fructose operon FruR; COG1349 Transcriptional regulators of sugar metabolism.
 
  
 0.981
AEN96297.1
COG1925 Phosphotransferase system, HPr-related proteins.
 
 
 0.979
AEN97586.1
COG1925 Phosphotransferase system, HPr-related proteins.
 
 
 0.979
AEN96145.1
Hypothetical protein; COG1925 Phosphotransferase system, HPr-related proteins.
  
 
 0.976
AEN97747.1
COG1925 Phosphotransferase system, HPr-related proteins.
  
 
 0.976
AEN95624.1
Fructose-1,6-bisphosphate aldolase, class II; COG0191 Fructose/tagatose bisphosphate aldolase.
 
 
 0.973
AEN96697.1
PTS system, N-acetylglucosamine-specific IIBC component; COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific.
 
  
 0.953
AEN96084.1
ROK family protein; COG1940 Transcriptional regulator/sugar kinase.
  
 
 0.947
AEN95806.1
COG3711 Transcriptional antiterminator.
 
  
 0.940
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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