Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN98327.1Hypothetical protein; COG0789 Predicted transcriptional regulators. (236 aa)    
Predicted Functional Partners:
AEN97730.1
COG1388 FOG: LysM repeat.
  
    0.769
AEN96925.1
Hypothetical protein.
  
    0.755
AEN95698.1
Hypothetical protein.
  
     0.745
AEN95585.1
Spore coat protein CotS related protein; COG2334 Putative homoserine kinase type II (protein kinase fold).
  
     0.729
AEN97457.1
Hypothetical protein.
  
     0.719
AEN97732.1
Hypothetical protein.
  
     0.713
AEN95854.1
Stage V sporulation protein AA.
  
     0.709
rpoZ
Hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
 
 
   0.709
AEN96009.1
COG3976 Uncharacterized protein conserved in bacteria.
  
     0.707
AEN95888.1
Peptidase S8/S53 subtilisin kexin sedolisin; COG1404 Subtilisin-like serine proteases.
  
     0.704
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
Server load: medium (54%) [HD]