Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
AEN98380.1Helix-turn-helix domain-containing protein; COG1396 Predicted transcriptional regulators. (110 aa)    
Predicted Functional Partners:
AEN98378.1
Hypothetical protein; COG2972 Predicted signal transduction protein with a C-terminal ATPase domain.
       0.634
AEN98379.1
COG3279 Response regulator of the LytR/AlgR family.
     
 0.634
AEN98377.1
Hypothetical protein.
       0.438
AEN98381.1
Hypothetical protein.
       0.436
AEN98376.1
Accessory gene regulator B; COG4512 Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide.
       0.425
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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