STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AEN98479.1Two-component response regulator (extracellular proteinase response regulator); COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain. (214 aa)    
Predicted Functional Partners:
AEN98480.1
Histidine kinase; COG4585 Signal transduction histidine kinase.
 
 0.983
AEN95229.1
COG4585 Signal transduction histidine kinase.
 
 
 0.826
AEN95379.1
PAS/PAC sensor hybrid histidine kinase; COG0784 FOG: CheY-like receiver.
  
 
 0.803
AEN96120.1
COG0642 Signal transduction histidine kinase.
  
 
 0.723
AEN98481.1
COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
     
 0.511
AEN96314.1
COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.
 
 
 0.497
AEN95374.1
Hypothetical protein; COG0642 Signal transduction histidine kinase.
 
 
 0.451
AEN96313.1
COG0642 Signal transduction histidine kinase.
 
 
 0.446
AEN96391.1
Diguanylate cyclase/phosphodiesterase; COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain.
 
 
 0.425
AEN95174.1
Winged helix family two component transcriptional regulator; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
 
 0.409
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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