Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEN98480.1Histidine kinase; COG4585 Signal transduction histidine kinase. (340 aa)    
Predicted Functional Partners:
AEN98479.1
Two-component response regulator (extracellular proteinase response regulator); COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
 
 0.983
AEN95230.1
Hypothetical protein; COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain.
 
 
 0.851
AEN98481.1
COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
       0.506
AEN97109.1
COG0515 Serine/threonine protein kinase.
 
  
 0.495
AEN95516.1
Hypothetical protein.
  
 
 0.413
AEN97167.1
Hypothetical protein.
  
 
 0.413
AEN97215.1
Hypothetical protein.
  
 
 0.413
AEN97283.1
Hypothetical protein.
  
 
 0.413
AEN97709.1
Hypothetical protein.
  
 
 0.413
AEN97824.1
Hypothetical protein.
  
 
 0.413
Your Current Organism:
Roseburia hominis
NCBI taxonomy Id: 585394
Other names: R. hominis A2-183, Roseburia hominis A2-183, Roseburia hominis str. A2-183, Roseburia hominis strain A2-183, butyrate-producing bacterium A2-183
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