STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lipALipoyl synthase, apicoplast; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (442 aa)    
Predicted Functional Partners:
PVX_122550
Lipoate-protein ligase, putative.
 
 
 0.986
PVX_092250
Lipoyl-binding domain-containing protein.
   
 0.983
PVX_099590
BPL/LPL catalytic domain-containing protein.
  
 
 0.952
PVX_089180
Lipoate-protein ligase, putative.
  
  
 0.726
PVX_003745
Transporter, putative.
      
 0.685
PVX_111005
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
  
  
 0.675
PVX_083005
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
   
  
 0.659
PVX_084685
Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
      0.650
PVX_114225
tRNA modifying enzyme, putative.
     
 0.632
PVX_003740
SufE domain-containing protein.
    
 
 0.628
Your Current Organism:
Plasmodium vivax
NCBI taxonomy Id: 126793
Other names: P. vivax Sal-1, Plasmodium vivax (STRAIN SAL-I), Plasmodium vivax (strain Salvador I), Plasmodium vivax SaI-1, Plasmodium vivax Sal-1, Plasmodium vivax Salvador I
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