STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PVX_089705ATPase ASNA1 homolog; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] (374 aa)    
Predicted Functional Partners:
PVX_118565
Uncharacterized protein.
    
 0.999
PVX_094805
DNA repair protein RAD23, putative.
   
 0.958
PVX_122475
Ubiquitin domain containing protein.
   
 0.798
PVX_095230
Vesicle transport protein Sec22, putative; Belongs to the synaptobrevin family.
   
 
 0.789
PVX_089275
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
    
 0.784
PVX_084620
Polyubiquitin 5, putative.
    
 0.782
PVX_091315
Ubiquitin domain containing protein.
   
 0.782
PVX_092205
Ubiquitin domain containing protein.
   
 0.782
PVX_099520
Ubiquitin-like protein, putative.
   
 0.782
PVX_086305
Ribosomal S27a, putative.
    
 0.777
Your Current Organism:
Plasmodium vivax
NCBI taxonomy Id: 126793
Other names: P. vivax Sal-1, Plasmodium vivax (STRAIN SAL-I), Plasmodium vivax (strain Salvador I), Plasmodium vivax SaI-1, Plasmodium vivax Sal-1, Plasmodium vivax Salvador I
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.