node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEJ52268.1 | fmt | HMPREF6123_0459 | HMPREF6123_0457 | Putative ribosomal RNA small subunit methyltransferase B; COG: COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.999 |
EEJ52268.1 | nusA | HMPREF6123_0459 | HMPREF6123_0325 | Putative ribosomal RNA small subunit methyltransferase B; COG: COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | 0.931 |
EEJ52268.1 | rlmN | HMPREF6123_0459 | HMPREF6123_0460 | Putative ribosomal RNA small subunit methyltransferase B; COG: COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.968 |
EEJ52268.1 | rplM | HMPREF6123_0459 | HMPREF6123_1689 | Putative ribosomal RNA small subunit methyltransferase B; COG: COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.891 |
EEJ52268.1 | rpoB | HMPREF6123_0459 | HMPREF6123_0043 | Putative ribosomal RNA small subunit methyltransferase B; COG: COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.938 |
EEJ52268.1 | rpsJ | HMPREF6123_0459 | HMPREF6123_0147 | Putative ribosomal RNA small subunit methyltransferase B; COG: COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.931 |
EEJ52268.1 | stp | HMPREF6123_0459 | HMPREF6123_0461 | Putative ribosomal RNA small subunit methyltransferase B; COG: COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Serine/threonine phosphatase stp; COG: COG0631. | 0.894 |
EEJ52268.1 | thiI | HMPREF6123_0459 | HMPREF6123_1066 | Putative ribosomal RNA small subunit methyltransferase B; COG: COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Thiamine biosynthesis/tRNA modification protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.907 |
EEJ52268.1 | truB | HMPREF6123_0459 | HMPREF6123_0332 | Putative ribosomal RNA small subunit methyltransferase B; COG: COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.906 |
EEJ52268.1 | ylqF | HMPREF6123_0459 | HMPREF6123_0678 | Putative ribosomal RNA small subunit methyltransferase B; COG: COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.946 |
fmt | EEJ52268.1 | HMPREF6123_0457 | HMPREF6123_0459 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Putative ribosomal RNA small subunit methyltransferase B; COG: COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.999 |
fmt | rlmN | HMPREF6123_0457 | HMPREF6123_0460 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | 0.871 |
fmt | stp | HMPREF6123_0457 | HMPREF6123_0461 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Serine/threonine phosphatase stp; COG: COG0631. | 0.869 |
nusA | EEJ52268.1 | HMPREF6123_0325 | HMPREF6123_0459 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Putative ribosomal RNA small subunit methyltransferase B; COG: COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.931 |
nusA | rplM | HMPREF6123_0325 | HMPREF6123_1689 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.930 |
nusA | rpoB | HMPREF6123_0325 | HMPREF6123_0043 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.986 |
nusA | rpsJ | HMPREF6123_0325 | HMPREF6123_0147 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.971 |
nusA | truB | HMPREF6123_0325 | HMPREF6123_0332 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.859 |
nusA | ylqF | HMPREF6123_0325 | HMPREF6123_0678 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.459 |
rlmN | EEJ52268.1 | HMPREF6123_0460 | HMPREF6123_0459 | 23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. | Putative ribosomal RNA small subunit methyltransferase B; COG: COG0144; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.968 |