STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEJ52219.1N-6 DNA Methylase; COG: COG0286. (500 aa)    
Predicted Functional Partners:
EEJ52218.1
Hypothetical protein.
 
 0.997
EEJ50906.1
Hypothetical protein.
  
 
 0.984
EEJ52213.1
Hypothetical protein.
  
 
 0.971
EEJ52214.1
Helicase C-terminal domain protein; COG: COG4096.
 
 
 0.969
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.648
EEJ50651.1
Restriction endonuclease.
 
  
 0.644
FbpA
Fibronectin-binding protein A domain protein; COG: COG1293.
  
    0.613
dcm
DNA (cytosine-5-)-methyltransferase; COG: COG0270.
  
 
 0.554
guaA
GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP.
     
 0.550
EEJ50843.1
Hypothetical protein; COG: COG1106.
  
    0.533
Your Current Organism:
Oribacterium sinus
NCBI taxonomy Id: 585501
Other names: O. sinus F0268, Oribacterium sinus F0268, Oribacterium sinus str. F0268, Oribacterium sinus strain F0268
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