node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEJ51421.1 | EEJ51422.1 | HMPREF6123_1337 | HMPREF6123_1338 | ATPase, AAA family; COG: COG2256. | Hypothetical protein. | 0.403 |
EEJ51421.1 | EEJ51799.1 | HMPREF6123_1337 | HMPREF6123_0954 | ATPase, AAA family; COG: COG2256. | Competence/damage-inducible domain protein CinA; COG: COG1546; Belongs to the CinA family. | 0.534 |
EEJ51421.1 | EEJ52193.1 | HMPREF6123_1337 | HMPREF6123_0538 | ATPase, AAA family; COG: COG2256. | Putative YigZ family protein; COG: COG1739. | 0.416 |
EEJ51421.1 | EEJ52260.1 | HMPREF6123_1337 | HMPREF6123_0451 | ATPase, AAA family; COG: COG2256. | FtsK/SpoIIIE family protein; COG: COG1674. | 0.649 |
EEJ51421.1 | dnaN | HMPREF6123_1337 | HMPREF6123_1402 | ATPase, AAA family; COG: COG2256. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.456 |
EEJ51421.1 | guaA | HMPREF6123_1337 | HMPREF6123_0500 | ATPase, AAA family; COG: COG2256. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.497 |
EEJ51421.1 | nadE | HMPREF6123_1337 | HMPREF6123_0759 | ATPase, AAA family; COG: COG2256. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.710 |
EEJ51421.1 | polA | HMPREF6123_1337 | HMPREF6123_0587 | ATPase, AAA family; COG: COG2256. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.657 |
EEJ51422.1 | EEJ51421.1 | HMPREF6123_1338 | HMPREF6123_1337 | Hypothetical protein. | ATPase, AAA family; COG: COG2256. | 0.403 |
EEJ51799.1 | EEJ51421.1 | HMPREF6123_0954 | HMPREF6123_1337 | Competence/damage-inducible domain protein CinA; COG: COG1546; Belongs to the CinA family. | ATPase, AAA family; COG: COG2256. | 0.534 |
EEJ51799.1 | EEJ52260.1 | HMPREF6123_0954 | HMPREF6123_0451 | Competence/damage-inducible domain protein CinA; COG: COG1546; Belongs to the CinA family. | FtsK/SpoIIIE family protein; COG: COG1674. | 0.403 |
EEJ51799.1 | guaA | HMPREF6123_0954 | HMPREF6123_0500 | Competence/damage-inducible domain protein CinA; COG: COG1546; Belongs to the CinA family. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.413 |
EEJ51799.1 | nadE | HMPREF6123_0954 | HMPREF6123_0759 | Competence/damage-inducible domain protein CinA; COG: COG1546; Belongs to the CinA family. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.961 |
EEJ51799.1 | polA | HMPREF6123_0954 | HMPREF6123_0587 | Competence/damage-inducible domain protein CinA; COG: COG1546; Belongs to the CinA family. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.631 |
EEJ52193.1 | EEJ51421.1 | HMPREF6123_0538 | HMPREF6123_1337 | Putative YigZ family protein; COG: COG1739. | ATPase, AAA family; COG: COG2256. | 0.416 |
EEJ52260.1 | EEJ51421.1 | HMPREF6123_0451 | HMPREF6123_1337 | FtsK/SpoIIIE family protein; COG: COG1674. | ATPase, AAA family; COG: COG2256. | 0.649 |
EEJ52260.1 | EEJ51799.1 | HMPREF6123_0451 | HMPREF6123_0954 | FtsK/SpoIIIE family protein; COG: COG1674. | Competence/damage-inducible domain protein CinA; COG: COG1546; Belongs to the CinA family. | 0.403 |
EEJ52260.1 | guaA | HMPREF6123_0451 | HMPREF6123_0500 | FtsK/SpoIIIE family protein; COG: COG1674. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.698 |
EEJ52260.1 | polA | HMPREF6123_0451 | HMPREF6123_0587 | FtsK/SpoIIIE family protein; COG: COG1674. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.718 |
dnaN | EEJ51421.1 | HMPREF6123_1402 | HMPREF6123_1337 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATPase, AAA family; COG: COG2256. | 0.456 |