STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrBAspartate carbamoyltransferase; COG: COG0540; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (308 aa)    
Predicted Functional Partners:
pyrI
Aspartate carbamoyltransferase regulatory chain, allosteric domain protein; COG: COG1781.
 
 0.999
pyrC
Amidohydrolase family protein; COG: COG0044.
 0.999
hydA
Dihydropyrimidinase; COG: COG0044.
 
 0.998
EEJ52350.1
Hypothetical protein.
  
 
 0.990
pyrDB
Dihydroorotate dehydrogenase 1B; Catalyzes the conversion of dihydroorotate to orotate.
 
 
 0.987
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
  
 0.984
pyrK
Oxidoreductase NAD-binding domain protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
 
 
 0.969
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
  
 0.955
EEJ50368.1
Putative permease; COG: COG2233.
 
  
 0.949
arcC
Carbamate kinase; COG: COG0549; Belongs to the carbamate kinase family.
    
 0.913
Your Current Organism:
Oribacterium sinus
NCBI taxonomy Id: 585501
Other names: O. sinus F0268, Oribacterium sinus F0268, Oribacterium sinus str. F0268, Oribacterium sinus strain F0268
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.