STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rihBPyrimidine-specific ribonucleoside hydrolase RihB; COG: COG1957. (310 aa)    
Predicted Functional Partners:
rbsK
Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
 
 0.942
EEJ50726.1
Putative ribokinase; COG: COG0524.
 
 0.862
hpt
Hypoxanthine phosphoribosyltransferase; COG: COG0634; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
     
 0.822
EEJ50580.1
Hypothetical protein.
     
 0.818
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.817
xpt
Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.
     
 0.817
EEJ50272.1
Transcriptional regulator, Sir2 family; COG: COG0846.
   
 
 0.807
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
   
 0.797
argE
Peptidase, ArgE/DapE family; COG: COG0624.
 
    0.784
EEJ52477.1
Putative selenium metabolism protein SsnA; COG: COG0402.
    
 0.740
Your Current Organism:
Oribacterium sinus
NCBI taxonomy Id: 585501
Other names: O. sinus F0268, Oribacterium sinus F0268, Oribacterium sinus str. F0268, Oribacterium sinus strain F0268
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