node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEJ50272.1 | EEJ50580.1 | HMPREF6123_2463 | HMPREF6123_2154 | Transcriptional regulator, Sir2 family; COG: COG0846. | Hypothetical protein. | 0.913 |
EEJ50272.1 | rihB | HMPREF6123_2463 | HMPREF6123_1976 | Transcriptional regulator, Sir2 family; COG: COG0846. | Pyrimidine-specific ribonucleoside hydrolase RihB; COG: COG1957. | 0.807 |
EEJ50580.1 | EEJ50272.1 | HMPREF6123_2154 | HMPREF6123_2463 | Hypothetical protein. | Transcriptional regulator, Sir2 family; COG: COG0846. | 0.913 |
EEJ50580.1 | rihB | HMPREF6123_2154 | HMPREF6123_1976 | Hypothetical protein. | Pyrimidine-specific ribonucleoside hydrolase RihB; COG: COG1957. | 0.818 |
EEJ50726.1 | apt | HMPREF6123_1984 | HMPREF6123_0082 | Putative ribokinase; COG: COG0524. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.510 |
EEJ50726.1 | rbsK | HMPREF6123_1984 | HMPREF6123_1973 | Putative ribokinase; COG: COG0524. | Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.885 |
EEJ50726.1 | rihB | HMPREF6123_1984 | HMPREF6123_1976 | Putative ribokinase; COG: COG0524. | Pyrimidine-specific ribonucleoside hydrolase RihB; COG: COG1957. | 0.862 |
EEJ50726.1 | xpt | HMPREF6123_1984 | HMPREF6123_0780 | Putative ribokinase; COG: COG0524. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.510 |
EEJ52477.1 | apt | HMPREF6123_0233 | HMPREF6123_0082 | Putative selenium metabolism protein SsnA; COG: COG0402. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.817 |
EEJ52477.1 | hpt | HMPREF6123_0233 | HMPREF6123_1518 | Putative selenium metabolism protein SsnA; COG: COG0402. | Hypoxanthine phosphoribosyltransferase; COG: COG0634; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.828 |
EEJ52477.1 | rihB | HMPREF6123_0233 | HMPREF6123_1976 | Putative selenium metabolism protein SsnA; COG: COG0402. | Pyrimidine-specific ribonucleoside hydrolase RihB; COG: COG1957. | 0.740 |
EEJ52477.1 | xpt | HMPREF6123_0233 | HMPREF6123_0780 | Putative selenium metabolism protein SsnA; COG: COG0402. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.817 |
apt | EEJ50726.1 | HMPREF6123_0082 | HMPREF6123_1984 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative ribokinase; COG: COG0524. | 0.510 |
apt | EEJ52477.1 | HMPREF6123_0082 | HMPREF6123_0233 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative selenium metabolism protein SsnA; COG: COG0402. | 0.817 |
apt | hpt | HMPREF6123_0082 | HMPREF6123_1518 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine phosphoribosyltransferase; COG: COG0634; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.919 |
apt | rbsK | HMPREF6123_0082 | HMPREF6123_1973 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.422 |
apt | rihB | HMPREF6123_0082 | HMPREF6123_1976 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Pyrimidine-specific ribonucleoside hydrolase RihB; COG: COG1957. | 0.817 |
apt | xpt | HMPREF6123_0082 | HMPREF6123_0780 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.949 |
argE | rbsK | HMPREF6123_1975 | HMPREF6123_1973 | Peptidase, ArgE/DapE family; COG: COG0624. | Putative ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.688 |
argE | rihB | HMPREF6123_1975 | HMPREF6123_1976 | Peptidase, ArgE/DapE family; COG: COG0624. | Pyrimidine-specific ribonucleoside hydrolase RihB; COG: COG1957. | 0.784 |