node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EER74277.1 | EER75754.1 | HMPREF0877_1556 | HMPREF0877_0061 | Putative ribosomal protein S1; COG: COG0539; Pfam: PF00575; InterPro: IPR003029. | Hypothetical protein; COG: COG1302; Pfam: PF03780; InterPro: IPR005531. | 0.439 |
EER74277.1 | efp | HMPREF0877_1556 | HMPREF0877_0062 | Putative ribosomal protein S1; COG: COG0539; Pfam: PF00575; InterPro: IPR003029. | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.529 |
EER74277.1 | metG | HMPREF0877_1556 | HMPREF0877_1952 | Putative ribosomal protein S1; COG: COG0539; Pfam: PF00575; InterPro: IPR003029. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.579 |
EER74277.1 | nusA | HMPREF0877_1556 | HMPREF0877_1265 | Putative ribosomal protein S1; COG: COG0539; Pfam: PF00575; InterPro: IPR003029. | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | 0.813 |
EER74277.1 | nusB | HMPREF0877_1556 | HMPREF0877_0060 | Putative ribosomal protein S1; COG: COG0539; Pfam: PF00575; InterPro: IPR003029. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.633 |
EER74277.1 | nusG | HMPREF0877_1556 | HMPREF0877_0405 | Putative ribosomal protein S1; COG: COG0539; Pfam: PF00575; InterPro: IPR003029. | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | 0.740 |
EER74277.1 | rpoZ | HMPREF0877_1556 | HMPREF0877_0205 | Putative ribosomal protein S1; COG: COG0539; Pfam: PF00575; InterPro: IPR003029. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.664 |
EER74277.1 | rpsJ | HMPREF0877_1556 | HMPREF0877_0458 | Putative ribosomal protein S1; COG: COG0539; Pfam: PF00575; InterPro: IPR003029. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.985 |
EER75754.1 | EER74277.1 | HMPREF0877_0061 | HMPREF0877_1556 | Hypothetical protein; COG: COG1302; Pfam: PF03780; InterPro: IPR005531. | Putative ribosomal protein S1; COG: COG0539; Pfam: PF00575; InterPro: IPR003029. | 0.439 |
EER75754.1 | efp | HMPREF0877_0061 | HMPREF0877_0062 | Hypothetical protein; COG: COG1302; Pfam: PF03780; InterPro: IPR005531. | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.653 |
EER75754.1 | nusB | HMPREF0877_0061 | HMPREF0877_0060 | Hypothetical protein; COG: COG1302; Pfam: PF03780; InterPro: IPR005531. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.874 |
efp | EER74277.1 | HMPREF0877_0062 | HMPREF0877_1556 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Putative ribosomal protein S1; COG: COG0539; Pfam: PF00575; InterPro: IPR003029. | 0.529 |
efp | EER75754.1 | HMPREF0877_0062 | HMPREF0877_0061 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Hypothetical protein; COG: COG1302; Pfam: PF03780; InterPro: IPR005531. | 0.653 |
efp | metG | HMPREF0877_0062 | HMPREF0877_1952 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. | 0.586 |
efp | nusA | HMPREF0877_0062 | HMPREF0877_1265 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | 0.721 |
efp | nusB | HMPREF0877_0062 | HMPREF0877_0060 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.674 |
efp | nusG | HMPREF0877_0062 | HMPREF0877_0405 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | 0.568 |
efp | rpoZ | HMPREF0877_0062 | HMPREF0877_0205 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.527 |
efp | rpsJ | HMPREF0877_0062 | HMPREF0877_0458 | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.995 |
fmt | folD | HMPREF0877_0938 | HMPREF0877_0213 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.975 |