node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EER74803.1 | EER74804.1 | HMPREF0877_0955 | HMPREF0877_0956 | S4 domain protein; COG: COG2302; Pfam: PF01479; InterPro: IPR002942. | YGGT family protein; Pfam: PF02325; InterPro: IPR003425. | 0.919 |
EER74803.1 | divIB | HMPREF0877_0955 | HMPREF0877_0960 | S4 domain protein; COG: COG2302; Pfam: PF01479; InterPro: IPR002942. | Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | 0.634 |
EER74803.1 | divIVA | HMPREF0877_0955 | HMPREF0877_0954 | S4 domain protein; COG: COG2302; Pfam: PF01479; InterPro: IPR002942. | DivIVA domain protein; COG: COG3599; Pfam: PF05103; InterPro: IPR007793. | 0.825 |
EER74803.1 | ftsA | HMPREF0877_0955 | HMPREF0877_0959 | S4 domain protein; COG: COG2302; Pfam: PF01479; InterPro: IPR002942. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.772 |
EER74803.1 | ftsZ | HMPREF0877_0955 | HMPREF0877_0958 | S4 domain protein; COG: COG2302; Pfam: PF01479; InterPro: IPR002942. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.901 |
EER74803.1 | murD | HMPREF0877_0955 | HMPREF0877_0962 | S4 domain protein; COG: COG2302; Pfam: PF01479; InterPro: IPR002942. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.557 |
EER74803.1 | murG | HMPREF0877_0955 | HMPREF0877_0961 | S4 domain protein; COG: COG2302; Pfam: PF01479; InterPro: IPR002942. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.640 |
EER74803.1 | sepF | HMPREF0877_0955 | HMPREF0877_0957 | S4 domain protein; COG: COG2302; Pfam: PF01479; InterPro: IPR002942. | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | 0.938 |
EER74804.1 | EER74803.1 | HMPREF0877_0956 | HMPREF0877_0955 | YGGT family protein; Pfam: PF02325; InterPro: IPR003425. | S4 domain protein; COG: COG2302; Pfam: PF01479; InterPro: IPR002942. | 0.919 |
EER74804.1 | divIB | HMPREF0877_0956 | HMPREF0877_0960 | YGGT family protein; Pfam: PF02325; InterPro: IPR003425. | Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | 0.677 |
EER74804.1 | divIVA | HMPREF0877_0956 | HMPREF0877_0954 | YGGT family protein; Pfam: PF02325; InterPro: IPR003425. | DivIVA domain protein; COG: COG3599; Pfam: PF05103; InterPro: IPR007793. | 0.908 |
EER74804.1 | ftsA | HMPREF0877_0956 | HMPREF0877_0959 | YGGT family protein; Pfam: PF02325; InterPro: IPR003425. | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. | 0.801 |
EER74804.1 | ftsZ | HMPREF0877_0956 | HMPREF0877_0958 | YGGT family protein; Pfam: PF02325; InterPro: IPR003425. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.897 |
EER74804.1 | murD | HMPREF0877_0956 | HMPREF0877_0962 | YGGT family protein; Pfam: PF02325; InterPro: IPR003425. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.453 |
EER74804.1 | murG | HMPREF0877_0956 | HMPREF0877_0961 | YGGT family protein; Pfam: PF02325; InterPro: IPR003425. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.501 |
EER74804.1 | sepF | HMPREF0877_0956 | HMPREF0877_0957 | YGGT family protein; Pfam: PF02325; InterPro: IPR003425. | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | 0.965 |
atpA | ftsZ | HMPREF0877_0497 | HMPREF0877_0958 | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.667 |
divIB | EER74803.1 | HMPREF0877_0960 | HMPREF0877_0955 | Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | S4 domain protein; COG: COG2302; Pfam: PF01479; InterPro: IPR002942. | 0.634 |
divIB | EER74804.1 | HMPREF0877_0960 | HMPREF0877_0956 | Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | YGGT family protein; Pfam: PF02325; InterPro: IPR003425. | 0.677 |
divIB | divIVA | HMPREF0877_0960 | HMPREF0877_0954 | Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily. | DivIVA domain protein; COG: COG3599; Pfam: PF05103; InterPro: IPR007793. | 0.630 |