STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFK55189.1DNA polymerase III, epsilon subunit. (341 aa)    
Predicted Functional Partners:
EFK53641.1
Hypothetical protein; 2.7.7.7.
  
  
  0.967
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.962
dnaX
DNA polymerase III, subunit gamma and tau; COG: COG2812; Pfam: PF00004; InterPro: IPR012763.
   
 0.961
dnaE
DNA polymerase III subunit alpha; COG: COG0587; Pfam: PF02811,PF07733,PF01336; InterPro: IPR004805.
    
  0.953
holA
DNA polymerase III, delta subunit; COG: COG1466; Pfam: PF06144; InterPro: IPR005790.
    
  0.944
EFK55141.1
DNA polymerase III, delta' subunit; COG: COG0470.
   
  0.918
EFK54110.1
Exonuclease; Pfam: PF00929; InterPro: IPR006055.
  
  
  0.907
EFK55190.1
Mur ligase middle domain protein; COG: COG0769; Pfam: PF08245,PF08353; InterPro: IPR013221.
 
     0.850
EFK55191.1
CobB/CobQ-like protein; COG: COG3442; Pfam: PF07685; InterPro: IPR011698.
       0.829
dnaE2
DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
    
  0.814
Your Current Organism:
Corynebacterium genitalium
NCBI taxonomy Id: 585529
Other names: C. genitalium ATCC 33030, Corynebacterium genitalium ATCC 33030, Corynebacterium genitalium NCTC 11859, Corynebacterium genitalium str. ATCC 33030, Corynebacterium genitalium strain ATCC 33030
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.