STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EFK54654.1Cys/Met metabolism PLP-dependent enzyme; COG: COG0626; Pfam: PF01053; InterPro: IPR000277. (396 aa)    
Predicted Functional Partners:
cysK
Cysteine synthase A; COG: COG0031; Pfam: PF00291; InterPro: IPR005859; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.991
EFK54742.1
Aminotransferase, class I/II; COG: COG1168; Pfam: PF00155; InterPro: IPR015421.
 
 
 0.965
EFK55298.1
Putative 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.961
EFK55503.1
Nitrite/sulfite reductase ferredoxin domain protein; COG: COG0155; Pfam: PF03460,PF01077; InterPro: IPR006067; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 0.955
metX
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
 
  
 0.954
EFK54195.1
Homoserine dehydrogenase; COG: COG0460; Pfam: PF03447,PF00742,PF01842; InterPro: IPR001342.
  
 
 0.954
EFK55535.1
Rhodanese-like protein; COG: COG2897; Pfam: PF00581; InterPro: IPR001763.
  
 
 0.931
ilvA
Threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.931
EFK54898.1
O-acetylhomoserine aminocarboxypropyltransferase; COG: COG2873; Pfam: PF01053; InterPro: IPR006235.
 
 
0.930
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.928
Your Current Organism:
Corynebacterium genitalium
NCBI taxonomy Id: 585529
Other names: C. genitalium ATCC 33030, Corynebacterium genitalium ATCC 33030, Corynebacterium genitalium NCTC 11859, Corynebacterium genitalium str. ATCC 33030, Corynebacterium genitalium strain ATCC 33030
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