node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EFK53641.1 | EFK54110.1 | HMPREF0291_11298 | HMPREF0291_11767 | Hypothetical protein; 2.7.7.7. | Exonuclease; Pfam: PF00929; InterPro: IPR006055. | 0.906 |
EFK53641.1 | EFK54151.1 | HMPREF0291_11298 | HMPREF0291_11808 | Hypothetical protein; 2.7.7.7. | Exonuclease; Pfam: PF00929; InterPro: IPR006055. | 0.920 |
EFK53641.1 | EFK55141.1 | HMPREF0291_11298 | HMPREF0291_10399 | Hypothetical protein; 2.7.7.7. | DNA polymerase III, delta' subunit; COG: COG0470. | 0.926 |
EFK53641.1 | EFK55189.1 | HMPREF0291_11298 | HMPREF0291_10447 | Hypothetical protein; 2.7.7.7. | DNA polymerase III, epsilon subunit. | 0.967 |
EFK53641.1 | dnaE | HMPREF0291_11298 | HMPREF0291_11286 | Hypothetical protein; 2.7.7.7. | DNA polymerase III subunit alpha; COG: COG0587; Pfam: PF02811,PF07733,PF01336; InterPro: IPR004805. | 0.963 |
EFK53641.1 | dnaE2 | HMPREF0291_11298 | HMPREF0291_10171 | Hypothetical protein; 2.7.7.7. | DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.855 |
EFK53641.1 | dnaN | HMPREF0291_11298 | HMPREF0291_10584 | Hypothetical protein; 2.7.7.7. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.971 |
EFK53641.1 | dnaX | HMPREF0291_11298 | HMPREF0291_10452 | Hypothetical protein; 2.7.7.7. | DNA polymerase III, subunit gamma and tau; COG: COG2812; Pfam: PF00004; InterPro: IPR012763. | 0.971 |
EFK53641.1 | holA | HMPREF0291_11298 | HMPREF0291_11100 | Hypothetical protein; 2.7.7.7. | DNA polymerase III, delta subunit; COG: COG1466; Pfam: PF06144; InterPro: IPR005790. | 0.956 |
EFK53641.1 | polA | HMPREF0291_11298 | HMPREF0291_11722 | Hypothetical protein; 2.7.7.7. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.903 |
EFK54110.1 | EFK53641.1 | HMPREF0291_11767 | HMPREF0291_11298 | Exonuclease; Pfam: PF00929; InterPro: IPR006055. | Hypothetical protein; 2.7.7.7. | 0.906 |
EFK54110.1 | EFK55141.1 | HMPREF0291_11767 | HMPREF0291_10399 | Exonuclease; Pfam: PF00929; InterPro: IPR006055. | DNA polymerase III, delta' subunit; COG: COG0470. | 0.918 |
EFK54110.1 | EFK55189.1 | HMPREF0291_11767 | HMPREF0291_10447 | Exonuclease; Pfam: PF00929; InterPro: IPR006055. | DNA polymerase III, epsilon subunit. | 0.907 |
EFK54110.1 | dnaE | HMPREF0291_11767 | HMPREF0291_11286 | Exonuclease; Pfam: PF00929; InterPro: IPR006055. | DNA polymerase III subunit alpha; COG: COG0587; Pfam: PF02811,PF07733,PF01336; InterPro: IPR004805. | 0.953 |
EFK54110.1 | dnaE2 | HMPREF0291_11767 | HMPREF0291_10171 | Exonuclease; Pfam: PF00929; InterPro: IPR006055. | DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.814 |
EFK54110.1 | dnaN | HMPREF0291_11767 | HMPREF0291_10584 | Exonuclease; Pfam: PF00929; InterPro: IPR006055. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.962 |
EFK54110.1 | dnaX | HMPREF0291_11767 | HMPREF0291_10452 | Exonuclease; Pfam: PF00929; InterPro: IPR006055. | DNA polymerase III, subunit gamma and tau; COG: COG2812; Pfam: PF00004; InterPro: IPR012763. | 0.961 |
EFK54110.1 | holA | HMPREF0291_11767 | HMPREF0291_11100 | Exonuclease; Pfam: PF00929; InterPro: IPR006055. | DNA polymerase III, delta subunit; COG: COG1466; Pfam: PF06144; InterPro: IPR005790. | 0.944 |
EFK54110.1 | polA | HMPREF0291_11767 | HMPREF0291_11722 | Exonuclease; Pfam: PF00929; InterPro: IPR006055. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.411 |
EFK54151.1 | EFK53641.1 | HMPREF0291_11808 | HMPREF0291_11298 | Exonuclease; Pfam: PF00929; InterPro: IPR006055. | Hypothetical protein; 2.7.7.7. | 0.920 |